Lookup NU author(s): Professor Stephen Rushton,
Emeritus Professor Michael Goodfellow,
Professor Anthony O'Donnell,
Professor John Magee
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The incidence of infection by mycobacteria, other than tubercle bacilli (MOTT) is increasing in the United Kingdom, Europe and the United States. These diseases increase morbidity and are an increasing public health concern. However, the epidemiology of disease due to these species is not well characterized. We used space-time clustering approaches and Generalized Linear Modelling to investigate the potential predictors of disease in cases of infection by organisms of the Mycobacterium avium complex (MAC) and M. malmoense recorded in the north of England during 2000-2005. There was significant spatial and temporal clustering in juvenile cases of infection by MAC but not for cases of infection in adults by either species. There were no significant predictors of infection by M. malmoense or juvenile cases of M. avium. Incidence of disease caused by M. avium in adults was significantly related to health deprivation and weakly related to rainfall. We consider possible reasons for the difference in epidemiology in infection by M. avium in adults and juveniles. © 2006 Cambridge University Press.
Author(s): Rushton SP, Goodfellow M, O'Donnell AG, Magee JG
Publication type: Article
Publication status: Published
Journal: Epidemiology and Infection
Print publication date: 01/06/2007
ISSN (print): 0950-2688
ISSN (electronic): 1469-4409
Publisher: Cambridge University Press
PubMed id: 17083748
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