Lookup NU author(s): Dr Simon Doherty,
Dr Julian Knight,
Dr Ross Harrington,
Emeritus Professor Bill Clegg
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
(Chemical Equation Presented) Rhodium-catalyzed double [2 + 2 + 2] cycloaddition of 1,4-bis(diphenylphosphinoyl)buta-1,3-diyne with tethered diynes provides a straightforward, single-pot procedure for the synthesis of a new class of tropos biaryl diphosphine, NU-BIPHEP. This methodology represents a significant improvement on existing multistep procedures. Enantiopure Lewis acid platinum complexes of these diphosphines are highly efficient catalysts for carbonyl-ene and Diels-Alder reactions, and ruthenium diphosphine-diamine complexes catalyze the asymmetric reduction of ketones to give ee's that rival those obtained with their BINAP counterpart. © 2007 American Chemical Society.
Author(s): Doherty S, Knight JG, Smyth CH, Harrington RW, Clegg W
Publication type: Letter
Publication status: Published
Journal: Organic Letters
ISSN (print): 1523-7060
ISSN (electronic): 1523-7052