Lookup NU author(s): Dr Charles Kelly,
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Background. Head and neck sarcomas are extremely rare. This article reviews the management and outcomes in a multidisciplinary clinic. Methods. The records of 41 male and 19 female patients (mean age, 50 years) were reviewed. Forty percent underwent surgical resection only, 35% underwent surgery and adjuvant therapy, and 25% underwent radiotherapy and/or chemotherapy without surgery. Seventy-one percent had complete histologic clearance. Results. The mean follow-up was 3 years and 10 months, with an overall 5-year survival rate of 60%. Completeness of surgical excision was highly significant in determining 5-year local control (p <.025), and the addition of adjuvant radiotherapy had a major effect on local control, but only if complete surgical clearance had been achieved (p <.025). As expected, patients with more aggressive tumors had a significantly poorer overall prognosis, and achieving local control led to an enhanced 5-year survival (p <.025). Conclusion. These tumors are best managed in multidisciplinary clinics, and the mainstay of treatment is wide local excision and planned postoperative adjuvant radiotherapy. (c) 2005 Wiley Periodicals, Inc.
Author(s): Colville RJ, Chariton F, Kelly CG, Nicoll JJ, McLean NR
Publication type: Conference Proceedings (inc. Abstract)
Publication status: Published
Conference Name: Head & Neck: Summer Meeting of the British Association of Plastic Surgeons
Year of Conference: 2005
Publisher: John Wiley & Sons, Inc.
Library holdings: Search Newcastle University Library for this item