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Browsing publications by Professor Martin Noble

Newcastle AuthorsTitleYearFull text
Duncan Miller
Dr Mathew Martin
Santosh Adhikari
Alfie Brennan
Professor Jane Endicott
et al.
Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach2018
Dr Mathew Martin
Professor Martin Noble
Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor2018
Judith Unterlass
Dr Arnaud Basle
Dr Julie Tucker
Dr Celine Cano
Professor Martin Noble
et al.
Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer2018
Dr Dominic Jones
Professor Martin Noble
Professor Steve Wedge
Professor Craig Robson
Dr Luke Gaughan
et al.
Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer2017
Christopher Coxon
Dr Suzannah Harnor
Dr Mathew Martin
Dr Benoit Carbain
Professor Bernard Golding
et al.
Cyclin-Dependent Kinase (CDK) Inhibitors; Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines2017
Stephen Hallett
Dr Martyna Pastok
Dr Anita Wittner
Professor Steve Wedge
Professor Martin Noble
et al.
Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System2017
Professor David Rees
Professor Bernard Golding
Dr Ian Hardcastle
Dr Celine Cano
Duncan Miller
et al.
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICANCER ACTIVITY2017
Professor David Rees
Professor Bernard Golding
Dr Ian Hardcastle
Dr Celine Cano
Duncan Miller
et al.
Preparation of isoindolinones as inhibitors of the MDM2-​p53 interaction having anticancer activity2017
Judith Unterlass
Dr Arnaud Basle
Dr Julie Tucker
Dr Celine Cano
Professor Martin Noble
et al.
Structural insights into the enzymatic activity and potential substrate promiscuity of human 3-phosphoglycerate dehydrogenase (PHGDH)2017
Dr Mathew Martin
Professor Jane Endicott
Professor Martin Noble
Structure-based discovery of cyclin-dependent protein kinase inhibitors2017
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