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Browsing publications by Professor Martin Noble

Newcastle AuthorsTitleYearFull text
Professor Martin Noble
Announcing mandatory submission of PDBx/mmCIF format files for crystallographic depositions to the protein data bank (PDB)2019
Daniel Wood
Svitlana Korolchuk
Dr Natalie Tatum
Lan Wang
Professor Jane Endicott
et al.
Differences in the conformational energy landscape of CDK1 and CDK2 suggest a mechanism for achieving selective CDK inhibition2019
Daniel Wood
Daniel Lopez Fernandez
Leanne Knight
Islam Al-Khawaldeh
Conghao Gai
et al.
FragLites - minimal, halogenated fragments displaying pharmacophore doublets. An efficient approach to druggability assessment and hit generation2019
Stephanie Myers
Duncan Miller
Dr Lauren Molyneux
Dr Mercedeh Arasta
Dr Ruth Bawn
et al.
Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD42019
Duncan Miller
Dr Mathew Martin
Santosh Adhikari
Alfie Brennan
Professor Jane Endicott
et al.
Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach2018
Dr Mathew Martin
Professor Martin Noble
Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor2018
Judith Unterlass
Dr Arnaud Basle
Dr Julie Tucker
Dr Celine Cano
Professor Martin Noble
et al.
Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer2018
Dr Dominic Jones
Professor Martin Noble
Professor Steve Wedge
Professor Craig Robson
Dr Luke Gaughan
et al.
Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer2017
Christopher Coxon
Dr Suzannah Harnor
Dr Mathew Martin
Dr Benoit Carbain
Professor Bernard Golding
et al.
Cyclin-Dependent Kinase (CDK) Inhibitors; Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines2017
Stephen Hallett
Dr Martyna Pastok
Dr Anita Wittner
Professor Steve Wedge
Professor Martin Noble
et al.
Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System2017
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