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Browsing publications by Dr Karen Haggerty.

Newcastle AuthorsTitleYearFull text
Dr Ian Hardcastle
Dr Ruth Bawn
Dr Tim Blackburn
Dr Celine Cano
Dr Sarah Cully
et al.
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction2021
Dr Benoit Carbain
Dr Allyson Campbell
Dr Celine Cano
Professor Jane Endicott
Emeritus Professor Bernard Golding
et al.
8-Substituted O-6-Cyclohexylmethylguanine CDK2 Inhibitors: Using Structure-Based Inhibitor Design to Optimize an Alternative Binding Mode2014
Alex Liu
Dr Catherine Drummond
Professor Jane Endicott
Emeritus Professor Bernard Golding
Professor Roger Griffin
et al.
An X-ray crystal structure-based understanding of the inhibition of the MDM2-p53 protein-protein interaction by isoindolinones2014
Tom Winstanley
Dr Karen Haggerty
Dr Corinne Wills
Emeritus Professor Bill Clegg
Dr Ross Harrington
et al.
Axially Chiral BODIPYs2014
Dr Tommy Rennison
Faye Craven
Emeritus Professor Bernard Golding
Professor Roger Griffin
Dr Karen Haggerty
et al.
Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives2012
Dr Ian Hardcastle
Alex Liu
Dr Eric Valeur
Anna Watson
Shafiq Ahmed
et al.
Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein-Protein Interaction: Structure-Activity Studies Leading to Improved Potency2011
Dr Karim Bennaceur
Dr Catherine Drummond
Professor Jane Endicott
Emeritus Professor Bernard Golding
Professor Roger Griffin
et al.
MDM2-p53 protein-protein interaction inhibitors: A-ring substituted isoindolinones2011
Dr Celine Cano
Emeritus Professor Bernard Golding
Dr Karen Haggerty
Dr Ian Hardcastle
Professor Roger Griffin
et al.
Atropisomeric 8-arylchromen-4-ones exhibit enantioselective inhibition of the DNA-dependent protein kinase (DNA-PK)2010
Dr Francesco Marchetti
Dr Celine Cano
Professor Nicola Curtin
Emeritus Professor Bernard Golding
Professor Roger Griffin
et al.
Synthesis and biological evaluation of 5-substituted O4-alkylpyrimidines as CDK2 inhibitors2010
Dr Celine Cano
Professor Nicola Curtin
Emeritus Professor Bernard Golding
Dr Karen Haggerty
Dr Ian Hardcastle
et al.
Development of Potent Water-soluble Inhibitors of DNA-Dependent Protein Kinase (DNA-PK)2008
Dr Kappusamy Saravanan
Dr Celine Cano
Professor Nicola Curtin
Emeritus Professor Bernard Golding
Dr Karen Haggerty
et al.
Identification of potent water-soluble DNA-dependent protein kinase (DNA-PK) inhibitors using a small-molecule library approach [abstract]2008
Dr Francesco Marchetti
Kerry Louise Sayle
Dr Johanne Bentley
Emeritus Professor Bill Clegg
Professor Nicola Curtin
et al.
Structure-based design of 2-arylamino-4-cyclohexylmethoxy-5-nitroso-6- aminopyrimidine inhibitors of cyclin-dependent kinase 22007