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Browsing publications by Paul Thompson

Newcastle AuthorsTitleYearFull text
Paul Thompson
Professor Alastair Hawkins
Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme2019
Paul Thompson
Professor Alastair Hawkins
Synthesis of rigidified shikimic acid derivatives by ring-closing metathesis to imprint inhibitor efficacy against shikimate kinase enzyme2019
Dr Arnaud Basle
Dr Lorraine Hewitt
Dr Heather Lamb
Paul Thompson
Professor Grant Burgess
et al.
Crystal structure of NucB, a biofilm-degrading endonuclease2018
Dr David Wilkinson
Angie Habgood
Dr Heather Lamb
Paul Thompson
Professor Alastair Hawkins
et al.
Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms2017
Paul Thompson
Professor Alastair Hawkins
Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study2017
Dr David Wilkinson
Hua Lin
Sarah Charlton
Dr Adrian Falconer
Dr Craig Bullock
et al.
The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: Molecular mechanisms and implications for extracellular matrix turnover2017
Paul Thompson
Professor Alastair Hawkins
Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme2016
Paul Thompson
Professor Alastair Hawkins
Frontispiece: Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme2016
Paul Thompson
Professor Alastair Hawkins
Study of the Phosphoryl-Transfer Mechanism of Shikimate Kinase by NMR Spectroscopy2016
Paul Thompson
Professor Alastair Hawkins
Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme2016
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