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Browsing publications by Professor Penny Lovat

Newcastle AuthorsTitleYearFull text
Dr Chiao-En Wu
Tsin Koay
Professor Penny Lovat
Professor John Lunec
TP53 mutant cell lines selected for resistance to MDM2 inhibitors retain growth inhibition by MAPK pathway inhibitors but a reduced apoptotic response2019
Dr Chiao-En Wu
Tsin Koay
Arman Esfandiari
Professor Penny Lovat
Professor John Lunec
et al.
ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma2019
Dr Robert Ellis
Dr Diana Tang
Dr Batoul Nasr
Alison Greenwood
Dr Ashleigh McConnell
et al.
Epidermal autophagy and beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I melanomas2019
Dr John Widdrington
Dr Aurora Gomez Duran
Dr Angela Pyle
Dr Marie Ruchaud-Sparagano
Jonathan Scott
et al.
Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses2018
Dr Stamatina Verykiou
Michael Alexander
Dr Noel Edwards
Professor Penny Lovat
Dr David Hill
et al.
Harnessing autophagy to overcome MEK-inhibitor induced resistance in metastatic melanoma2018
Arman Esfandiari
Nan Wang
Dr Ahmed Mahdi
Erhan Aptullahoglu
Professor Penny Lovat
et al.
Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeuticstrategy in cutaneous melanoma2018
Dr Francesco Zummo
Kirsty Cullen
Minna Honkanen-Scott
Professor James Shaw
Professor Penny Lovat
et al.
Glucagon-like peptide-1 protects pancreatic beta-cells from death by increasing autophagic flux and restoring lysosomal function2017
Dr Bernadette Carroll
Dr Glyn Nelson
Dr Yoana Rabanal Ruiz
Dr Olena Kucheryavenko
Professor Penny Lovat
et al.
Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing2017
Dr Jane Renwick
Christopher McKee
Professor Penny Lovat
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization.2016
Dr Francesco Zummo
Kirsty Cullen
Professor Penny Lovat
Professor James Shaw
Dr Catherine Arden
et al.
Glucagon-like peptide-1 requires EPAC activity to restore autophagy and protect pancreatic beta cells from cell death2016
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