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Browsing publications by Dr Gavin Richardson.

Newcastle AuthorsTitleYearFull text
Dr Maria Camacho Encina
Laura Booth
Dr Rachael Redgrave
Dr Omowumi Folaranmi
Professor Ioakim Spyridopoulos
et al.
Cellular Senescence, Mitochondrial Dysfunction, and Their Link to Cardiovascular Disease2024
Dr Rachael Redgrave
Dr Anna Walaszczyk
Micheylla Dewi
Dr Maria Camacho Encina
Dr Gavin Richardson
et al.
The effect of varying irrigation flow-rate during irrigated radiofrequency ablation on optimising lesion shape2024
Dr Bilal Bawamia
Dr Luke Spray
Vincent Wangsaputra
Dr Karim Bennaceur
Dr Sharareh Vahabi
et al.
Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction Randomized Pilot Trial2023
Dr Kateryna Sopova
Dr Simon Tual-Chalot
Dr Nikolaos Vlachogiannis
Dr Georgios Georgiopoulos
Dr Luke Spray
et al.
Effector T cell chemokine IP-10 predicts cardiac recovery and clinical outcomes post-myocardial infarction2023
Shu Xian Loh
Yasemin Ekinci
Dr Luke Spray
Dr Visvesh Jeyalan
Dr Gavin Richardson
et al.
Fractalkine Signalling (CX3CL1/CX3CR1 Axis) as an Emerging Target in Coronary Artery Disease.2023
Laura Booth
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Professor Ioakim Spyridopoulos
Dr Helen Phillips
et al.
Heart Disease and Ageing: The Roles of Senescence, Mitochondria, and Telomerase in Cardiovascular Disease2023
Dr Maria Camacho Encina
Dr Rachael Redgrave
Dr Gavin Richardson
Identifying older donor hearts suitable for transplantation: the use of senescence as a marker of biological age2023
Professor Miles Witham
Dr Antoneta Granic
Dr Satomi Miwa
Dr Gavin Richardson
Professor Avan Sayer
et al.
New Horizons in cellular senescence for clinicians2023
Dr Rachael Redgrave
Dr Emily Dookun
Laura Booth
Dr Maria Camacho Encina
Dr Omowumi Folaranmi
et al.
Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction2023
Dr Rachael Redgrave
Dr Maria Camacho Encina
Dr Simon Tual-Chalot
Dr Omowumi Folaranmi
Dr Carmen Martin-Ruiz
et al.
The senescence-associated secretory phenotype as a biomarker for age-related myocardial remodelling and cardiovascular disease2023
Professor Ioakim Spyridopoulos
Dr Bilal Bawamia
Dr Luke Spray
Vincent Wangsaputra
Professor Konstantinos Stellos
et al.
Activation of mitochondrial telomerase reverses relative lymphopenia post myocardial infarction: results from the randomised, double-blinded TACTIC phase IIa pilot trial2022
Laura Booth
Dr Rachael Redgrave
Dr Omowumi Folaranmi
Dr Gavin Richardson
Anthracycline-induced cardiotoxicity and senescence2022
Rachel Oldershaw
Dr Gavin Richardson
Pip Carling
Dr Andrew Owens
Dr Annette Meeson
et al.
Cardiac Mesenchymal Stem Cell-like Cells Derived from a Young Patient with Bicuspid Aortic Valve Disease Have a Prematurely Aged Phenotype2022
Dr Anna Walaszczyk
Dr Emily Dookun
Dr Rachael Redgrave
Dr Pawel Palmowski
Dr Simon Tual-Chalot
et al.
Therapeutic potential of navitoclax in age-related cardiovascular diseases2022
Emily Dookun
Dr Joao Passos
Professor Helen Arthur
Dr Gavin Richardson
Therapeutic Potential of Senolytics in Cardiovascular Disease2022
Jose Coelho Lima Junior
Dr Georgios Georgiopoulos
Dr Jannath Ahmed
David Gaskin
Dr Konstantinos Bakogiannis
et al.
Prognostic value of admission high-sensitivity troponin in patients with ST-elevation myocardial infarction2021
Dr Andrew Owens
Dr Anna Walaszczyk
Professor Ioakim Spyridopoulos
Dr Emily Dookun
Dr Gavin Richardson
et al.
Senescence and Senolytics in Cardiovascular disease: Promise and Potential Pitfalls2021
Jedrzej Hoffmann
Dr Gavin Richardson
Professor Ioakim Spyridopoulos
Telomerase As a Therapeutic Target in Cardiovascular Disease2021
Dr Catherine Park
Dr Suzanne Cormack
Dr Ashfaq Mohammed
Dr Stephen Boag
Dr Karim Bennaceur
et al.
The Fractalkine Receptor CX3CR1 Links Lymphocyte Kinetics in CMV-Seropositive Patients and Acute Myocardial Infarction With Adverse Left Ventricular Remodeling2021
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Pawel Palmowski
Dr Simon Tual-Chalot
et al.
Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery2020
Dr Carmen Martin-Ruiz
Professor Thomas von Zglinicki
Dr Gavin Richardson
Lilia Draganova
Dr Rachael Redgrave
et al.
CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians2020
Danlin Liu
Dr Gavin Richardson
Fehmi Benli
Dr Catherine Park
Joao Victor de De Souza Cunha
et al.
Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies2020
Dr Catherine Park
Dr Suzanne Cormack
Dr Stephen Boag
Dr Karim Bennaceur
Dr Gavin Richardson
et al.
Role of CMV-serostatus and CX3CR1 on lymphocyte kinetics and left ventricular remodelling in patients with acute myocardial infarction2020
Micheylla Dewi
Dr Anna Walaszczyk
Dr Gavin Richardson
Continuous Reduction In Irrigation Rate During Irrigated Radiofrequency Catheter Ablation Results In A More Optimised Lesion Shape Through Reduced Endocardial Sparing2019
Dr Rachel Oldershaw
Dr Andrew Owens
Rachel Telfer-Sutherland
Martin Linney
Rachel Liddle
et al.
Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential2019
Rhys Anderson
Anthony Lagnado
Damien Maggiorani
Dr Anna Walaszczyk
Emily Dookun
et al.
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence2019
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Oliver Yausep
et al.
Navitoclax eliminates senescence attenuating remodelling and improving outcome to cardiac ischemia-reperfusion injury2019
Dr Anna Walaszczyk
Emily Dookun
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Professor Ioakim Spyridopoulos
et al.
Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction.2019
Clara Correia Melo
Dr Jodie Birch
Dr Ed Fielder
Dr James Chapman
Dr Anthony Lagnado
et al.
Rapamycin improves healthspan but not inflammaging in nfkb1-/- mice2019
Oliver Yausep
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Simon Tual-Chalot
et al.
The Effects of Senolytics on Murine Cardiac Function and Morphology Post-Ischemia Reperfusion Injury2019
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Oliver Yausep
et al.
Accumulation of cardiomyocyte senescence following ischaemia-reperfusion injury (IRI); a potential therapeutic target?2018
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Oliver Yausep
et al.
Cardiomyocyte Senescence accumulates following Myocardial Infarction and Ischaemia-Reperfusion Injury.2018
Rhys Anderson
Dr Gavin Richardson
Dr Joao Passos
Mechanisms driving the ageing heart2018
Dr Anna Walaszczyk
Emily Dookun
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Rhys Anderson
et al.
Senescence as a therapeutic target for myocardial ageing2018
Dr Anna Walaszczyk
Emily Dookun
Dr Rachael Redgrave
Professor Ioakim Spyridopoulos
Professor Helen Arthur
et al.
Senescence contributes age related cardiac dysfunction2018
Dr Anna Walaszczyk
Emily Dookun
Dr Rachael Redgrave
Professor Ioakim Spyridopoulos
Professor Helen Arthur
et al.
Senescence contributes to reduced survival and impaired cardiac function following myocardial infraction in aged mice.2018
Dr Gavin Richardson
Dr Karim Bennaceur
Emily Dookun
Lilia Draganova
Dr Gabriele Saretzki
et al.
Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells2018
Damien Maggiorani
Dr Gavin Richardson
Dr Joao Passos
Young vs Old mouse cardiomyocytes RNA-Seq.2018
Kimberly Rockley
Dr Gavin Richardson
Dr Jason Gill
Characterisation of novel molecular mechanisms involved in anthracycline-induced cardiotoxicity2016
Dr Gavin Richardson
Professor Colin Jahoda
Contribution of GFP expressing Dermal Papillae cells to the formation of chimeric embryos and their survival in uterine environment.2016
Dr Gavin Richardson
Simultaneous Assessment of Cardiomyocyte DNA Synthesis and Ploidy: A Method to Assist Quantification of Cardiomyocyte Regeneration and Turnover2016
Professor Bob Anderson
Dr Simon Tual-Chalot
Dr Rachael Redgrave
Rebecca Dodds
Dr Andrew Owens
et al.
The role of cardiomyocyte senescence and regeneration in Ageing2016
Dr Gavin Richardson
Dr Steven Laval
Dr Andrew Owens
Cardiomyocyte regeneration in the mdx mouse model of non-ischemic cardiomyopathy2015
Dr Karim Bennaceur
Mark Atwill
Nayef Al Zhrany
Jedrzej Hoffmann
Professor Bernard Keavney
et al.
Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism2014
Dr Andrew Owens
Dr Gavin Richardson
Cardiomyocyte regeneration in non-ischaemic cardiomyopathy2014
Dr Annette Meeson
Andrew Fuller
Dr Andrew Owens
Dr Gavin Richardson
Optimised Protocols for the Identification of the Murine Cardiac Side Population2013
Dr Annette Meeson
Dr Steven Laval
Dr Andrew Owens
Dr Gavin Richardson
The Cardiac Side Population is Dynamic during the Progression of Cardiomyopathy in the mdx Model of DMD2013
Dr Gavin Richardson
Dr Annette Meeson
Dr Steven Laval
Andrew Fuller
Dr Andrew Owens
et al.
mTert Expression is Increased in the mdx Model of Cardiomyopathy2012
Dr Emma Bell
Dr Gavin Richardson
Professor Colin Jahoda
Dr Helen Phillips
Professor Deborah Henderson
et al.
Dermal stem cells can differentiate down an endothelial lineage2012
Dr Gavin Richardson
Dr Annette Meeson
Dr Steven Laval
Dr Andrew Owens
mTert Expression is Increased in the MDX Model of Cardiomyopathy2012
Craig Higgins
Dr Gavin Richardson
Professor Colin Jahoda
Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells2012
Dr Gavin Richardson
Dr Suzanne Cormack
Dr Andrew Owens
Telomerase expression in the mammalian heart2012
Dr Gavin Richardson
Professor Colin Jahoda
Modelling the hair follicle dermal papilla using spheroid cell cultures2010
Dr Gavin Richardson
Dr Nicholas Hole
Dr Andrew Owens
The Identification of Native Cardiac Stem Cells Based on Telomerase Activity2010
Dr Gavin Richardson
Dynamic expression of Syndecan-1 during hair follicle morphogenesis2009
Dr Gavin Richardson
Exogen involves gradual release of the hair club fibre in the vibrissa follicle model2009
Dr Gavin Richardson
Keratin 10 (K10) is expressed suprabasally throughout the limbus of embryonic and neonatal rat corneas, with interrupted expression in the adult limbus.2009
Dr Gavin Richardson
KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin2009
Dr Gavin Richardson
Multiple Properties of Hair Follicle Dermis Include Stem Cell Potential, Stem Cell Support, and Epithelial Reprogramming2009
Dr Gavin Richardson
Activation of EGF and FGF signaling in developing mouse skin inhibits hair follicle morphogenesis2007
Dr Gavin Richardson
Dr Amy Fearn
Professor Colin Jahoda
Hair and skin differentiation from the transit amplifying cells of the central cornea2007
Dr Gavin Richardson
Hair follicle stem cells2007
Dr Amy Fearn
Dr Gavin Richardson
Professor Colin Jahoda
Stem and developmental potential of the hair follicle – induction, regeneration, wound healing and stem cells2007
Dr Gavin Richardson
The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis2007
Dr Gavin Richardson
Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression2007
Dr Gavin Richardson
Determining the molecular basis of hair follicle induction.2006
Dr Gavin Richardson
Analysing the mechanisms of follicle dermal cell aggregation and induction: a cell and molecular study2005
Dr Gavin Richardson
Dr Clifford Lawrence
Dr Nicholas Hole
Professor Colin Jahoda
Cultured cells from the adult human hair follicle dermis can be directed toward adipogenic and osteogenic differentiation.2005
Dr Gavin Richardson
Dr Clifford Lawrence
Dr Nicholas Hole
Professor Colin Jahoda
Plasticity of rodent and human hair follicle dermal cells: Implications for cell therapy and tissue engineering2005
Dr Gavin Richardson
Professor Craig Robson
Professor David Neal
Dr Anne Collins
CD133, a novel marker for human prostatic epithelial stem cells2004
Dr Gavin Richardson
Dr Nicholas Hole
Stem cell potential of adult hair follicle dermal cells2004