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Browsing publications by Dr Roger Searle.

Newcastle AuthorsTitleYearFull text
Dr Harry Otun
Barbara Innes
Dr Gendie Lash
Dr Elizabeth Ball
Dr Roger Searle
et al.
Quantification of spiral artery remodelling using an Adobe Photoshop-based technique2019
Dr Craig Nesbitt
Professor Alexander Phillips
Dr Roger Searle
Professor Gerard Stansby
Randomized Trial to Assess the Effect of Supervised and Unsupervised Video Feedback on Teaching Practical Skills2015
Dr Meenakshi Swamy
Dr Hernaik Singh
Dr Roger Searle
Role of SimMan in teaching clinical skills to preclinical medical students2013
Dr Meenakshi Swamy
Dr Roger Searle
Anatomy teaching with portable ultrasound to medical students2012
Dr Dorota Overbeck-Zubrzycka
Amaran Krishnan
David Hamilton
Dr Roger Searle
Professor Gerard Stansby
et al.
Tomorrow’s Doctors: students’ satisfaction with a prosection-based undergraduate anatomy course2012
Dr Harry Otun
Dr Gendie Lash
Barbara Innes
Dr Judith Bulmer
Dr Katsuhiko Naruse
et al.
Effect of tumour necrosis factor-alpha in combination with interferon-gamma on first trimester extravillous trophoblast invasion2011
Dr Gendie Lash
Dr Katsuhiko Naruse
Dr Andrew Robson
Barbara Innes
Dr Roger Searle
et al.
Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production2011
Dr Gendie Lash
Dr Katsuhiko Naruse
Dr Andrew Robson
Barbara Innes
Dr Roger Searle
et al.
Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production2011
Dr Gendie Lash
Dr Harry Otun
Barbara Innes
Dr Roger Searle
Professor Steve Robson
et al.
Regulation of extravillous trophoblast invasion by uterine natural killer cells is dependent on gestational age2010
Dr Gendie Lash
Dr Judith Bulmer
Barbara Innes
Dr Roger Searle
Professor Steve Robson
et al.
Role of Interleukin 8 in Uterine Natural Killer Cell Regulation of Extravillous Trophoblast Cell Invasion2010
Dr Gendie Lash
Dr Katsuhiko Naruse
Barbara Innes
Professor Steve Robson
Dr Roger Searle
et al.
Secretion of Angiogenic Growth Factors by Villous Cytotrophoblast and Extravillous Trophoblast in Early Human Pregnancy2010
Dr Katsuhiko Naruse
Barbara Innes
Dr Judith Bulmer
Professor Steve Robson
Dr Roger Searle
et al.
Secretion of cytokines by villous cytotrophoblast and extravillous trophoblast in the first trimester of human pregnancy2010
Dr Judith Bulmer
Dr Roger Searle
Barbara Innes
Professor Steve Robson
Altered decidual leucocyte populations in the placental bed in pre-eclampsia and foetal growth restriction: a comparison with late normal pregnancy2009
Dr Roger Searle
Professor Steve Robson
Barbara Innes
Dr Judith Bulmer
Decidual leucocyte populations in early to late gestation normal human pregnancy2009
Dr Katsuhiko Naruse
Dr Gendie Lash
Barbara Innes
Dr Harry Otun
Dr Roger Searle
et al.
Localization of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitors for MMPs (TIMPs) in uterine natural killer cells in early human pregnancy2009
Dr Katsuhiko Naruse
Dr Gendie Lash
Dr Judith Bulmer
Barbara Innes
Dr Harry Otun
et al.
The Urokinase Plasminogen Activator (uPA) System in Uterine Natural Killer Cells in the Placental Bed During Early Pregnancy2009
Dr Leandro Oliveira
Dr Gendie Lash
Dr Judith Bulmer
Barbara Innes
Dr Roger Searle
et al.
HLA-G does not alter uterine natural killer cell secretion of cytokines2008
Dr Gendie Lash
Barbara Innes
Dr Roger Searle
Dr Judith Bulmer
uNK Cells Effect on Trophoblast Cell Invasion Involves IL-8 Secretion and the Mechanism of Action Involves Changes on Apoptosis2008
Dr Katsuhiko Naruse
Dr Gendie Lash
Barbara Innes
Dr Leandro Oliveira
Dr Harry Otun
et al.
Cytokine secretion by uterine natural killer cells in coculture with extravillous trophoblast2007
Dr Gendie Lash
Maureen Kirkley
Dr Roger Searle
Professor Steve Robson
Dr Judith Bulmer
et al.
Effect of Low Oxygen Concentrations on Trophoblast-Like Cell Line Invasion2007
Dr Roger Searle
Interleukin-17 Expression in the Human Placenta2007
Dr Leandro Oliveira
Dr Gendie Lash
Dr Harry Otun
Barbara Innes
Dr Katsuhiko Naruse
et al.
Uterine natural killer cell stimulation of trophoblast invasion is only partially dependent on IL-8 production2007
Dr Katsuhiko Naruse
Dr Gendie Lash
Barbara Innes
Dr Harry Otun
Dr Leandro Oliveira
et al.
Uterine natural killer cells disrupt vascular smooth muscle structure in vitro: A role in spiral artery remodelling?2007
Dr Gendie Lash
Barbara Innes
Dr Harry Otun
Professor Steve Robson
Dr Roger Searle
et al.
Comparison of three multiplex cytokine analysis systems: Luminex, SearchLight™ and FAST Quant®2006
Dr Judith Bulmer
Professor Steve Robson
Barbara Innes
Dr Roger Searle
Effector activity of decidual CD8+ T lymphocytes in early human pregnancy2006
Dr Gendie Lash
Maureen Kirkley
Barbara Innes
Dr Roger Searle
Professor Steve Robson
et al.
Expression of angiogenic growth factors by uterine natural killer cells during early pregnancy2006
Dr Gendie Lash
Dr Harry Otun
Barbara Innes
Maureen Kirkley
Dr Roger Searle
et al.
Interferon-γ inhibits extravillous trophoblast cell invasion by a mechanism that involves both changes in apoptosis and protease levels2006
Dr Katsuhiko Naruse
Dr Gendie Lash
Barbara Innes
Dr Judith Bulmer
Dr Harry Otun
et al.
Localization of proteases in uterine natural killer cells in the placental bed during early pregnancy2006
Dr Gendie Lash
Dr Harry Otun
Barbara Innes
Dr Judith Bulmer
Dr Roger Searle
et al.
Low oxygen concentrations inhibit trophoblast cell invasion from early gestation placental explants via alterations in levels of the urokinase plasminogen activator system2006
Dr Gendie Lash
Barbara Innes
Dr Roger Searle
Professor Steve Robson
Dr Judith Bulmer
et al.
Secretion of angiogenic growth factors by uterine natural killer cells.2006
Dr Katsuhiko Naruse
Dr Gendie Lash
Barbara Innes
Dr Judith Bulmer
Dr Roger Searle
et al.
Secretion of matrix metalloproteinase (MMP) 2 and 9 and urokinase plasminogen activator (uPA) by decidual cell fractions in early pregnancy2006
Dr Gendie Lash
Barbara Innes
Dr Judith Bulmer
Dr Roger Searle
Professor Steve Robson
et al.
Uterine natural killer cell cytokine secretion profile2006
Barbara Innes
Dr Gendie Lash
Professor Steve Robson
Dr Roger Searle
Dr Judith Bulmer
et al.
[abstract] Uterine NK cells persist after theist trimester but fewer express perforin and granzyme B2005
Paula Scaife
Dr Judith Bulmer
Barbara Innes
Professor Steve Robson
Dr Roger Searle
et al.
Assessment of the cytolytic capability of decidual CD8+T lymphocytes in normal early pregnancy2005
Dr Harry Otun
Dr Judith Bulmer
Dr Gendie Lash
Barbara Innes
Dr Roger Searle
et al.
Gestational changes in spiral artery vascular smooth muscle content using photoshop based image analysis2005
Dr Harry Otun
Dr Gendie Lash
Barbara Innes
Dr Roger Searle
Professor Steve Robson
et al.
Gestational changes in spiral artery vascular smooth muscle content using photoshop based image analysis2005
Dr Gendie Lash
Dr Harry Otun
Dr Judith Bulmer
Dr Roger Searle
Professor Steve Robson
et al.
Inhibition of extravillous trophoblast invasion by TGF-beta 1, 2 and 3 is associated with a reduction in secreted MMP-9 levels2005
Dr Gendie Lash
Dr Harry Otun
Barbara Innes
Dr Judith Bulmer
Dr Roger Searle
et al.
Inhibition of trophoblast cell invasion by TGFB1, 2, and 3 is associated with a decrease in active proteases2005
Dr Yoshiharu Sakamoto
Dr Judith Bulmer
Dr Roger Searle
Professor Steve Robson
Macrophages and not granulocytes are involved in cervical ripening2005
Dr Roger Searle
The role of decidual leucocytes in reproductive success in humans and other species2005
Dr Gendie Lash
Dr Harry Otun
Dr Judith Bulmer
Dr Roger Searle
Professor Steve Robson
et al.
TNF-alpha and IFN-gamma inhibit extravillous trophoblast invasion in a paracrine manner via a mechanism independent of MMP-2 or MMP-9 levels.2005
Paula Scaife
Dr Roger Searle
Professor Steve Robson
Barbara Innes
Dr Judith Bulmer
et al.
Comparison of decidual leucocyte populations in spontaneous early pregnancy loss.2004
Dr Gendie Lash
Dr Harry Otun
Barbara Innes
Dr Roger Searle
Dr Judith Bulmer
et al.
Culture of placental villous explants in 8% oxygen does not alter their invasive phenotype2004
Paula Scaife
Dr Roger Searle
Barbara Innes
Professor Steve Robson
Dr Judith Bulmer
et al.
Cytokine production by CD8+ decidual leucocytes in early pregnancy2004
Paula Scaife
Dr Roger Searle
Professor Steve Robson
Barbara Innes
Dr Judith Bulmer
et al.
Cytokine production by CD8+decidual leucocytes in early pregnancy2004
Dr Gendie Lash
Dr Harry Otun
Barbara Innes
Dr Roger Searle
Dr Judith Bulmer
et al.
Inhibition of extravillous trophoblast cell invasion in 3% oxygen is due to an increase in PAI-2 production2004
Dr Yoshiharu Sakamoto
Dr Roger Searle
Dr Judith Bulmer
Professor Steve Robson
Interleukin-8 is involved in cervical dilatation but not in prelabour cervical ripening2004
Dr Gendie Lash
Dr Harry Otun
Barbara Innes
Dr Judith Bulmer
Dr Roger Searle
et al.
Invasion of extravillous trophoblast cells is inhibited in low oxygen conditions2004
Dr Judith Bulmer
Dr Roger Searle
No evidence for apoptosis of decidual leucocytes in normal and molar pregnancy: Implications for immune privilege2004
Dr Roger Searle
Dr Judith Bulmer
Placental Fas and Fas ligand expression in normal early, term and molar pregnancy2004
Dr Harry Otun
Dr Gendie Lash
Barbara Innes
Dr Judith Bulmer
Dr Roger Searle
et al.
Regulation of trophoblast invasion by TGF-beta: Role of apoptosis and proliferation.2004
Paula Scaife
Dr Roger Searle
Professor Steve Robson
Barbara Innes
Dr Judith Bulmer
et al.
[abstract] A comparison of cytotoxic decidual lymphocytes in early and late pregnancy2003
Barbara Innes
Dr Roger Searle
Dr Judith Bulmer
Professor Steve Robson
[abstract] Use of laser capture microdissection and RT-PCR to study gene expression in heterogeneous differentiating trophoblast populations2003
Dr Harry Otun
Dr Gendie Lash
Dr Judith Bulmer
Dr Roger Searle
Professor Steve Robson
et al.
Inhibition of first trimester human extravillous trophoblast invasion by TNF-alpha and IFN-gamma2003
Dr Judith Bulmer
Barbara Innes
Dr Roger Searle
Professor Steve Robson
M30 is expressed by extravillous trophoblast in the placental bed in the first half of normal human pregnancy2003
Dr Harry Otun
Dr Roger Searle
Dr Judith Bulmer
Professor Steve Robson
The effect of gestational age on trophoblast invasion2003
Dr Harry Otun
Dr Roger Searle
Dr Judith Bulmer
Professor Steve Robson
The effect of TGF beta inhibition on trophoblast invasion2003
Dr Judith Bulmer
Dr Roger Searle
Lack of apoptotic decidual leucocytes in hydatidiform mole: no evidence for Fas-Fas ligand system mediated maternal T cell tolerance in molar pregnancy2002
Dr Roger Searle
Dr Judith Bulmer
Expression of Fas/Fas ligand by decidual leukocytes in hydatidiform mole2001
Dr Roger Searle
Dr Judith Bulmer
Maternal immune tolerance during molar pregnancy: increased expression of Fas ligand on abnormal trophoblast induces apoptosis of activated decidual leucocytes2001
Stephen Bromage
Dr Roger Searle
Abnormal TGFβ levels in the amniotic fluid of Down syndrome pregnancies2000
Dr Roger Searle
Stephen Bromage
Human amniotic fluid lacks interleukin-2 and interleukin-15 but can interact with the β-chain of the interleukin-2 receptor2000
Dr Roger Searle
Dr Judith Bulmer
Decidual T lymphocyte activation in hydatidiform mole1999
Dr Roger Searle
Dr Judith Bulmer
Elevated expression of activation molecules by decidual lymphocytes in women suffering spontaneous early pregnancy loss1999
Dr Roger Searle
Dr Judith Bulmer
Immunoregulatory activity of decidua in spontaneous early pregnancy loss1999
Dr Roger Searle
Dr Judith Bulmer
Phenotypic analysis and proliferative responses of human endometrial granulated lymphocytes during the menstrual cycle1999
Dr Roger Searle
Dr Judith Bulmer
Up-regulation of natural killer cell cytotoxicity by interleukin-2: The effect of sex and parity1999