Publications by Professor Deborah Henderson - ePrints

Browsing publications by Professor Deborah Henderson.

Newcastle Authors	Title	Year
Professor Bob Anderson Dr Simon Bamforth Dr Bill Chaudhry Dr Lorraine Eley Dr Janet Kerwin et al.	Development of the arterial roots and ventricular outflow tracts	2024
Dr Lorraine Eley Dr Rachel Richardson Ahlam Alqahtani Dr Bill Chaudhry Professor Deborah Henderson et al.	eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling	2024
Dr Chris Derrick Dr Ahlam Alqahtani Dr Lorraine Eley Professor Deborah Henderson Dr Bill Chaudhry et al.	Functional analysis of germline VANGL2 variants using rescue assays of vangl2 knockout zebrafish	2024
Professor Bob Anderson Professor Deborah Henderson	What are the conotruncal malformations?	2024
Professor Deborah Henderson	Editorial: Maternal-foetal crosstalk impacts on offspring development	2023
Dr Rachel Queen Moira Crosier Dr Lorraine Eley Dr Janet Kerwin Jasmin Turner et al.	Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves	2023
Issac Goh Kai'En Dr Rachel Botting Antony Rose Dr Simone Webb Justin Engelbert et al.	Yolk sac cell atlas reveals multiorgan functions during human early development	2023
Professor Deborah Henderson Dr Lorraine Eley Jasmin Turner Dr Bill Chaudhry	Development of the Human Arterial Valves: Understanding Bicuspid Aortic Valve	2022
Dr Chris Derrick Dr Adrian Santos Dr Lorraine Eley Bela Paramita Professor Deborah Henderson et al.	Sequential action of JNK genes establishes the embryonic left-right axis	2022
Dr Bill Chaudhry Dr Ahlam Alqahtani Dr Lorraine Eley Dr Louise Coats Dr Srinivas Annavarapu et al.	The Left Ventricular Myocardium in Hypoplastic Left Heart Syndrome	2022
Professor Bob Anderson Jasmin Turner Professor Deborah Henderson	The Morphogenesis of Abnormal Coronary Arteries in the Congenitally Malformed Heart	2022
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Sanja Bojic Nicky Moyse et al.	A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells	2021
Dr Laura Jardine Dr Simone Webb Issac Goh Dr Gary Reynolds Dr Michael Mather et al.	Blood and immune development in human fetal bone marrow and Down syndrome	2021
Dr Lindsay Murphy Dr Tamilvendhan Dhanaseelan Dr Lorraine Eley Dr David Burns Professor Deborah Henderson et al.	Exercise, programmed cell death and exhaustion of cardiomyocyte proliferation in aging zebrafish	2021
Professor Deborah Henderson	The editors’ personal biography of professor Robert Anderson	2021
Dr Rachel Botting Dr Cecilia Dominguez Conde Dr Dorin-Mirel Popescu Dr Emily Stephenson Dr Simone Webb et al.	A cell atlas of human thymic development defines T cell repertoire formation	2020
Dr Adrian Santos Sam Washer Dr Tamilvendhan Dhanaseelan Dr Lorraine Eley Dr Ahlam Alqahtani et al.	Alternative splicing of jnk1a in zebrafish determines first heart field ventricular cardiomyocyte numbers through modulation of hand2 expression	2020
Amy-Leigh Johnson Professor Deborah Henderson Dr Helen Phillips Dr Simon Bamforth	Early embryonic expression of AP-2a is critical for cardiovascular development	2020
Dr Ahlam Alqahtani Andrew Skelton Dr Lorraine Eley Dr Srinivas Annavarapu Professor Deborah Henderson et al.	Isolation and next generation sequencing of archival formalin-fixed DNA	2020
Professor Deborah Henderson Dr Lorraine Eley Dr Bill Chaudhry	New concepts in the development and malformation of the arterial valves	2020
Catherine Stothard Dr Silvia Mazzotta Professor Deborah Henderson Dr Helen Phillips Dr Simon Bamforth et al.	Pax9 and Gbx2 interact in the pharyngeal endoderm to control cardiovascular cevelopment.	2020
Professor Deborah Henderson	Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth	2020
Dr Claudia Racca Professor Deborah Henderson	Vangl2 in the Dentate Network Modulates Pattern Separation and Pattern Completion	2020
Dr Kate Bailey Dr Guy MacGowan Dr Simon Tual-Chalot Lauren Charlotte Phillips Phillips Professor Deborah Henderson et al.	Disruption of embryonic ROCK signalling reproduces the sarcomeric phenotype of Hypertrophic Cardiomyopathy	2019
Professor Deborah Henderson	VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland	2019
Dr Lorraine Eley Dr Ahlam Alqahtani Dr Rachel Richardson Dr Lindsay Murphy Shindi Tiurma et al.	A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice	2018
Dr Rachel Richardson Dr Lorraine Eley Charlotte Donald-Wilson Natasha Curley Dr Ahlam Alqahtani et al.	Development and maturation of the fibrous components of the arterial roots in the mouse heart	2018
Professor Deborah Henderson	Planar cell polarity in organ formation	2018
Professor Deborah Henderson	Vangl2 disruption alters the biomechanics of late spinal neurulation leading to spina bifida in mouse embryos	2018
Dr Kathryn White Professor Deborah Henderson	Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury	2018
Professor Bob Anderson Professor Deborah Henderson Dr Bill Chaudhry	Development and maintenance of the arterial valves	2017
Dr Ahlam Alqahtani Dr Rachel Richardson Dr John O'Sullivan Professor Bob Anderson Professor Deborah Henderson et al.	Re-evaluation of hypoplastic left heart syndrome from a developmental and morphological perspective	2017
Professor Bob Anderson Dr Simon Bamforth Professor Deborah Henderson Dr Bill Chaudhry	Development and maldevelopment of the ventricular outflow tracts	2016
Professor Deborah Henderson	The core planar cell polarity gene, Vangl2, directs adult corneal epithelial cell alignment and migration	2016
Professor Deborah Henderson Professor Bob Anderson	The anatomy and development of normal and abnormal coronary arteries	2015
Dr Bill Chaudhry David Burns Dr Lindsay Murphy Professor Deborah Henderson	Exercise and cardiomyocyte turnover in the aging zebrafish heart	2014
Dr Simon Ramsbottom Professor Deborah Henderson	Genetics of Cardiovascular Development	2014
Professor Bob Anderson Dr Simon Bamforth Nicola Brown Dr Bill Chaudhry Professor Deborah Henderson et al.	Myths and Realities Relating to Development of the Arterial Valves	2014
Professor Bob Anderson Dr Simon Bamforth Dr Bill Chaudhry Professor Deborah Henderson	Normal and abnormal development of the heart	2014
Dr Veronika Boczonadi Dr Iain Keenan Dr Simon Ramsbottom Charlotte Donald-Wilson Dr Bill Chaudhry et al.	Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium	2014
Professor Deborah Henderson Dr Simon Ramsbottom Vipul Sharma	Vangl2-regulated polarisation of second heart field cells is required for outflow tract lengthening	2014
Dr Simon Ramsbottom Vipul Sharma Dr Hong Jun Rhee Dr Lorraine Eley Dr Helen Phillips et al.	Vangl2-Regulated Polarisation of Second Heart Field-Derived Cells Is Required for Outflow Tract Lengthening during Cardiac Development	2014
Dr Nicola Hunt Professor Deborah Henderson	Calcium-Alginate Hydrogel-Encapsulated Fibroblasts Provide Sustained Release of Vascular Endothelial Growth Factor	2013
Dr Simon Bamforth Dr Bill Chaudhry Professor Deborah Henderson Professor Bob Anderson	Clarification of the identity of the mammalian fifth pharyngeal arch artery	2013
Addison Palomino Doza Dr Ana Topf Dr John O'Sullivan Professor Caroline Relton Professor Judith Goodship et al.	Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot	2013
Dr Helen Phillips Pavithra Mahendran Dr Esha Singh Professor Bob Anderson Dr Bill Chaudhry et al.	Neural crest cells are required for correct positioning of the developing outflow cushions and pattern the arterial valve leaflets	2013
Dr Bill Chaudhry David Burns Professor Deborah Henderson	Cardiomyocyte aging: swimming against the clock	2012
Professor Deborah Henderson Dr Veronika Boczonadi Dr Bill Chaudhry	Conditional deletion of Scrib gene in the developing myocardium leads to congenital heart defects	2012
Dr Emma Bell Dr Gavin Richardson Professor Colin Jahoda Dr Helen Phillips Professor Deborah Henderson et al.	Dermal stem cells can differentiate down an endothelial lineage	2012
Dr Nicola Hunt Antoniana Batsivari Dr Bill Chaudhry Professor Deborah Henderson	ECM control of neural crest cell (NCC) behaviour and implications for heart development	2012
Dr Bill Chaudhry Paul Chrystal Professor Deborah Henderson	Fast Digital Laser Sheet Microscopy: swimaging in 6 dimensions	2012
Dr Ana Topf Professor Judith Goodship Professor Deborah Henderson Dr John O'Sullivan Professor Bernard Keavney et al.	Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to congenital heart disease	2012
Dr Helen Phillips Tania Papoutsi Professor Deborah Henderson Dr Bill Chaudhry	Neural Crest Cell Survival is Dependent on Rho Kinase and is Required for Development of the Mid Face in Mouse Embryos	2012
Professor Bob Anderson Dr Bill Chaudhry Dr Simon Bamforth Dr Darren Hoyland Dr Helen Phillips et al.	Normal and abnormal development of the intrapericardial arterial trunks in humans and mice	2012
Dr Iain Keenan Dr Hong Jun Rhee Dr Bill Chaudhry Professor Deborah Henderson	Origin of non-cardiac endothelial cells from an Isl1+ lineage.	2012
Professor Deborah Henderson Dr Bill Chaudhry	Getting to the Heart of Planar Cell Polarity Signaling	2011
Professor Deborah Henderson	Kidins220/ARMS is an essential modulator of cardiovascular and nervous system development	2011
Dr Gordon Love Professor Deborah Henderson Dr Bill Chaudhry	Real-time optical gating for three-dimensional beating heart imaging	2011
Professor Bob Anderson Professor Deborah Henderson Dr Bill Chaudhry	Development of the outflow tracts with reference to aortopulmonary windows and aortoventricular tunnels	2010
Professor Deborah Henderson	Foregut separation and tracheo-oesophageal malformations: The role of tracheal outgrowth, dorso-ventral patterning and programmed cell death	2010
Professor Deborah Henderson	Inducible expression of ^V600EBraf using tyrosinase-driven Cre recombinase results in embryonic lethality	2010
Dr Helen Phillips Professor Deborah Henderson	Origins of Gliogenic Stem Cell Populations Within Adult Skin and Bone Marrow	2010
Professor Deborah Henderson	The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear	2010
Dr Andrew Robson Kathleen Allinson Professor Bob Anderson Professor Deborah Henderson Professor Helen Arthur et al.	The TGF beta Type II Receptor Plays a Critical Role in the Endothelial Cells During Cardiac Development	2010
Dr Helen Phillips Dr Veronika Boczonadi Dr Bill Chaudhry Professor Deborah Henderson	03-P015: Rho kinase is required for cohesive behaviour of neural crest cells during outflow tract morphogenesis	2009
Dr Victoria Hildreth Professor Bob Anderson Professor Deborah Henderson	Autonomic Innervation of the Developing Heart: Origins and Function	2009
Dr Veronika Boczonadi Professor Deborah Henderson Dr Bill Chaudhry	Cell traction force microscopy in cardiac morphogenesis	2009
Lucy Bradshaw Dr Bill Chaudhry Dr Victoria Hildreth Professor Deborah Henderson	Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutant Splotch(2H)	2009
Dr Victoria Hildreth Stephen Webb Dr Bill Chaudhry Dr Jonathan Peat Dr Helen Phillips et al.	Left cardiac isomerism in the Sonic hedgehog null mouse	2009
Professor Deborah Henderson Professor Bob Anderson	The Development and Structure of the Ventricles in the Human Heart	2009
Professor Deborah Henderson Professor Bob Anderson	The development and structure of the ventricles in the human heart	2009
Professor Deborah Henderson	Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression	2008
Dr Victoria Hildreth Lucy Bradshaw Professor Bob Anderson Professor Deborah Henderson	Cells migrating from the neural crest contribute to the innervation of the venous pole of the heart	2008
Professor Bob Anderson Professor Deborah Henderson	Lessons learnt with regard to aortopulmonary window	2008
Dr Helen Phillips Dr Victoria Hildreth Dr Jonathan Peat Dr Bill Chaudhry Professor Deborah Henderson et al.	Non-cell-autonomous roles for the planar cell polarity gene vangl2 in development of the coronary circulation	2008
Dr Helen Phillips Dr Hong Jun Rhee Dr Victoria Hildreth Dr Jonathan Peat Professor Bob Anderson et al.	Disruption of planar cell polarity signaling results in congenital heart defects and cardiomyopathy attributable to early cardiomyocyte disorganization	2007
Professor Deborah Henderson Dr Helen Phillips	Planar cell polarity signalling plays crucial roles in outflow tract development	2007
Dr Helen Phillips Professor Deborah Henderson	Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates	2006
Professor Deborah Henderson Dr Helen Phillips Dr Bill Chaudhry	Vang-like 2 and noncanonical Wnt signaling in outflow tract development	2006
Dr Victoria Hildreth Professor Deborah Henderson	An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes	2005
Dr Helen Phillips Professor Deborah Henderson	Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates	2005
Dr Victoria Hildreth Professor Deborah Henderson	Identification of cardiac abnormalities in the Sonic Hedgehog mouse mutant using optical projection tomography	2005
Dr Helen Phillips Professor Deborah Henderson	Role of the planar cell polarity pathway in the development of the outflow tract	2005
Dr Helen Phillips Dr Bill Chaudhry Professor Deborah Henderson	Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract	2005
Professor Deborah Henderson	Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system	2005
Professor Deborah Henderson	Coexpression of Brn-3a POU protein with p53 in a population of neuronal progenitor cells is associated with differentiation and protection against apoptosis	2004
Professor Deborah Henderson	Mechanisms regulating the initiation of neural tube closure	2004
Professor Bob Anderson Professor Deborah Henderson	Spatiotemporal Analysis of Programmed Cell Death during Mouse Cardiac Septation	2004
Professor Bob Anderson Professor Deborah Henderson	Spatio-temporal analysis of programmed cell death during mouse cardiac septation	2004
Professor Deborah Henderson Dr Helen Phillips	Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse	2003
Professor Deborah Henderson	Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse	2003
Professor Deborah Henderson	Role for Sonic hedgehog in the development of the trachea and the oesophagus	2003
Professor Judith Goodship Professor Deborah Henderson	Cardiac development and cardiovascular malformation	2002
Dr Steven Lisgo Professor Deborah Henderson Professor Tom Strachan Emerita Professor Susan Lindsay	Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia phenotype observed in CPx patients	2002
Dr Bill Chaudhry Professor Deborah Henderson	Dorsoventral patterning in oesophageal atresia with tracheo-oesophageal fistula: Evidence from a new mouse model	2002
Dr Simon Bamforth Francisco Marques Professor Deborah Henderson	Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a novel Tfap activator	2001
Professor Deborah Henderson Samantha Conway Professor Bob Anderson	Cardiovascular Defects Associated With Abnormalities in Midline Development in the Loop-tail Mouse Mutant	2001
Professor Deborah Henderson	Characterisation of the human TBX20 gene, a new member of the family closely related to the Drosophila H15 gene	2000
Professor Deborah Henderson	RhoB is expressed in migrating neural crest and endocardial cushions of the developing mouse embryo	2000
Professor Deborah Henderson Samantha Conway	Rib truncations and fusions in the Sp2H mouse reveal a role for Pax3 in specification of the posterior part of the somite	1999