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Browsing publications by Professor John Lunec

Newcastle AuthorsTitleYearFull text
Dr Nicholas Bown
Professor John Lunec
Professor Deborah Tweddle
Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group2020
Professor John Lunec
Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients2020
Professor John Lunec
Targeting P53 as a future strategy to overcome gemcitabine resistance in biliary tract cancers2020
Dr Chiao-En Wu
Tsin Koay
Professor Penny Lovat
Professor John Lunec
TP53 mutant cell lines selected for resistance to MDM2 inhibitors retain growth inhibition by MAPK pathway inhibitors but a reduced apoptotic response2019
Dr Chiao-En Wu
Tsin Koay
Arman Esfandiari
Professor Penny Lovat
Professor John Lunec
et al.
ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma2019
Dr Carmela Ciardullo
Erhan Aptullahoglu
Dr Laura Woodhouse
Dr Wei-Yu Lin
Dr Jonathan Wallis
et al.
Non-genotoxic MDM2 inhibition selectively induces pro-apoptotic p53 gene signature in chronic lymphocytic leukemia cells2019
Vahinipriya Manoharan
Professor John Lunec
Nucleotide variants and protein expression of TP53 in a Sri Lankan cohort of patients with head and neck cancer2019
Dr Lindi Chen
Philip Berry
Dr Jennifer Bonner
Calum Kirk
Dr Katrina Wood
et al.
Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma2019
Dr Yan Zhao
Professor John Lunec
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage2018
Honorine Lebraud
Dr Richard Noble
Nicole Phillips
Dr Yan Zhao
Emeritus Professor Herbie Newell
et al.
A highly potent clickable probe for cellular imaging of MDM2 and assessing dynamic responses to MDM2-p53 inhibition2018
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