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Browsing publications by
Suzanne Kyle
Newcastle Authors
Title
Year
Full text
Dr Catherine Willoughby
Huw Thomas
Dr Elaine Willmore
Suzanne Kyle
Dr Anita Wittner
et al.
Selective DNA-PKcs Inhibition Extends the Therapeutic Index of Localized Radiotherapy and Chemotherapy
2019
Carlo Bawn
Martin Galler
Huw Thomas
Suzanne Kyle
Professor Nicola Curtin
et al.
PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS
2017
James Murray
Huw Thomas
Philip Berry
Suzanne Kyle
Dr Miranda Morton
et al.
Tumour cell retention of rucaparib, sustained PARP inhibition and efficacy of weekly as well as daily schedules
2014
Michael Batey
Dr Yan Zhao
Suzanne Kyle
Emeritus Professor Herbie Newell
Professor Nicola Curtin
et al.
Preclinical Evaluation of a Novel ATM Inhibitor, KU59403,
In Vitro
and
In Vivo
in p53 Functional and Dysfunctional Models of Human Cancer
2013
Dr Emma Haagensen
Suzanne Kyle
Dr Gary Beale
Dr Ross Maxwell
Emeritus Professor Herbie Newell
et al.
The synergistic interaction of MEK and PI3K inhibitors is modulated by mTOR inhibition
2012
Huw Thomas
Suzanne Kyle
Ivanda Pavlovska
Professor Nicola Curtin
The Clinically Active PARP Inhibitor AG014699 Ameliorates Cardiotoxicity but Does Not Enhance the Efficacy of Doxorubicin, despite Improving Tumor Perfusion and Radiation Response in Mice
2011
Dr Yvette Drew
Dr Evan Mulligan
Wan Vong
Huw Thomas
Suzanne Kyle
et al.
Therapeutic Potential of Poly(ADP-ribose) Polymerase Inhibitor AG014699 in Human Cancers With Mutated or Methylated
BRCA1
or
BRCA2
2011
Huw Thomas
Suzanne Kyle
Rafal Zur
Dr Evan Mulligan
Professor Nicola Curtin
et al.
6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance
2010
Dr Asima Mukhopadhyay
Dr Ahmed Elattar
Dr Aiste McCormick
Sarah Wilkinson
Dr Yvette Drew
et al.
Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors
2010
Huw Thomas
Suzanne Kyle
Tim Robson
Professor Nicola Curtin
Vasoactivity of AG014699, a Clinically Active Small Molecule Inhibitor of Poly(ADP-ribose) Polymerase: a Contributory Factor to Chemopotentiation
In vivo
?
2009
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