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Browsing publications by Professor Jelena Mann.

Newcastle AuthorsTitleYearFull text
Laura Sabater
Jean-Baptiste Gossart
Inmaculada Hernandez Lopez
Dr Daniel Rico Rodriguez
Dr Lee Borthwick
et al.
miRNA Expression in Fibroblastic Foci within Idiopathic Pulmonary Fibrosis Lungs Reveals Novel Disease-Relevant Pathways2023
Dr Hany Zinad
Chanachai Sae-Lee
Mushtaq Khazeem
Amber Knox
Dr Git Chung
et al.
Interdependent Transcription of a Natural Sense/Antisense Transcripts Pair (SLC34A1/PFN3)2022
Dr Stella Breininger
Laura Sabater
Dr Fiona Malcomson
Sorena Afshar
Professor Jelena Mann
et al.
Obesity and Roux-en-Y gastric bypass drive changes in miR-31 and miR-215 expression in the human rectal mucosa2022
Dr Jack Leslie
Dr Hannah Paish
Amy Collins
Rebecca Scott
Abi Watson
et al.
A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis2021
Marina Barcena-Varela
Dr Hannah Paish
Stuart Robinson
Jeremy French
Professor Fiona Oakley
et al.
Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: Dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis2021
Professor Jelena Mann
Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases2021
Dr Julie Worrell
Dr Jack Leslie
Dr Graham Smith
Marco Zaki
Dr Hannah Paish
et al.
cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis2020
Dr Jack Leslie
Dr Marina Garcia Macia
Dr Saimir Luli
Dr Julie Worrell
William Reilly
et al.
c-Rel orchestrates energy-dependant epithelial and macrophage reprogramming in fibrosis2020
Laura Sabater
Dr Luigi Locatelli
Professor Fiona Oakley
Dr Timothy Hardy
Jeremy French
et al.
RNA sequencing reveals changes in the microRNAome of transdifferentiating hepatic stellate cells that are conserved between human and rat2020
John Moir
Anna Long
Dr Beate Haugk
Jeremy French
Richard Charnley
et al.
Therapeutic Strategies Toward Lactate Dehydrogenase Within the Tumor Microenvironment of Pancreatic Cancer2020
Dr Hannah Paish
Lee Reed
Helen Brown
Mark Bryan
Dr Olivier Govaere
et al.
A bioreactor technology for modelling fibrosis in human and rodent precision-cut liver slices2019
Dr Hannah Paish
Lee Reed
Abi Watson
Dr Jack Leslie
Professor Fiona Oakley
et al.
Ammonia Scavenging Prevents Progression of Fibrosis in Experimental Nonalcoholic Fatty Liver Disease2019
Professor Jelena Mann
Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis2019
Dr Eva Moran Salvador
Dr Ashwin Sivaharan
Laura Sabater
Marco Zaki
Amber Knox
et al.
Fibrogenic Activity of MECP2 is Regulated by Phosphorylation in Hepatic Stellate Cells2019
Rhys Anderson
Anthony Lagnado
Damien Maggiorani
Dr Anna Walaszczyk
Emily Dookun
et al.
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence2019
Dr Maria Perugorria
Professor Fiona Oakley
Professor Jelena Mann
Dr Dina Tiniakos
Professor Derek Mann
et al.
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage2019
Clara Correia Melo
Dr Jodie Birch
Dr Ed Fielder
Dr James Chapman
Dr Anthony Lagnado
et al.
Rapamycin improves healthspan but not inflammaging in nfkb1-/- mice2019
Stuart Robinson
Professor Jelena Mann
Richard Charnley
Systemic inflammation contributes to impairment of quality of life in chronic pancreatitis2019
Dr Tyrell Cartwright
Dr Julie Worrell
Letizia Marchetti
Amber Knox
Professor Jelena Mann
et al.
HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression2018
Professor Jelena Mann
Professor Helen Reeves
Liquid biopsy for liver diseases2018
Dr Marie Boyle
Faik Tutucu
Dr Timothy Hardy
Professor Derek Mann
Dr Mujdat Zeybel
et al.
Plasma cell-free DNA methylation: a liquid biomarker of hepatic fibrosis2018
Dr Mujdat Zeybel
Dr Saimir Luli
Laura Sabater
Dr Timothy Hardy
Professor Fiona Oakley
et al.
A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A2017
Dr Eva Moran Salvador
Professor Jelena Mann
Epigenetics and Liver Fibrosis2017
Professor Jelena Mann
Epigenetics in Liver Disease: Involvement of Oxidative Stress2017
Dr Timothy Hardy
Dr Mujdat Zeybel
Professor Chris Day
Dr Christian Dipper
Dr Steven Masson
et al.
Plasma DNA methylation: A potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease2017
Laura Corbett
Dr Pier Paoli
John Casement
Professor Jelena Mann
Professor Derek Mann
et al.
Variant Histone H2afv reprograms DNA methylation during early zebrafish development2017
Dr Lee Borthwick
Wona Suwara
Dr Sonya Carnell
Dr Nicola Green
Dr Rahul Mahida
et al.
Pseudomonas aeruginosa induced Airway Epithelial Injury Drives Fibroblast Activation: A Mechanism in Chronic Lung Allograft Dysfunction2016
Dr Mujdat Zeybel
Dr Timothy Hardy
Gemma Zeybel
Dr Matthew Bashton
Professor John Mathers
et al.
DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease2016
Professor Jelena Mann
Professor Derek Mann
Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFα stimulation regulates DNA binding and transcription2016
Dr Agata Page
Dr Pier Paoli
Dr Eva Moran Salvador
Steven White
Jeremy French
et al.
Hepatic stellate cell transdifferentiation involves genome-wide remodeling of the DNA methylation landscape2016
John Moir
Professor Derek Mann
Professor Jelena Mann
Richard Charnley
Professor Derek Manas
et al.
Metabolic relationships within the tumour microenvironment of pancreatic ductal adenocarcinoma - pancreatic stellate cells induce glycolysis in cancer cells2016
Stuart Robinson
Professor Derek Mann
Professor Derek Manas
Professor Fiona Oakley
Professor Jelena Mann
et al.
Response to 'Comment on 'The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndrome''2016
John Moir
Professor Derek Mann
Professor Jelena Mann
Richard Charnley
Professor Derek Manas
et al.
The effect of monocarboxylate transporter 1 inhibition in the tumour microenvironment of pancreatic ductal adenocarcinoma2016
Stuart Robinson
Steven White
Richard Charnley
Professor Jelena Mann
The role of exosomes in the pathogenesis of pancreatic ductal adenocarcinoma2016
Dr Agata Page
Dr Pier Paoli
Dr Stephen Hill
Rachel Howarth
Jeremy French
et al.
Alcohol directly stimulates epigenetic modifications in hepatic stellate cells2015
Dr Agata Page
Professor Jelena Mann
Professor Derek Mann
Changes in DNA methylation and hydroxymethylation during HSC activation2015
Dr Mujdat Zeybel
Dr Timothy Hardy
Stuart Robinson
Christopher Fox
Professor Quentin Anstee
et al.
Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease2015
Professor Jelena Mann
Professor Derek Mann
Epigenetic regulation of hepatic stellate cells and liver fibrosis2015
Dr Katherine Crossland
Dr Chun Chan
Tariq AlShehri
Dr Mario Abinun
Professor Andrew Gennery
et al.
Gain-of-function STAT1 mutations impair STAT3 activity in patients with Chronic Mucocutaneous Candidiasis (CMC)2015
Dr Timothy Hardy
Victoria Sharkey
Dr Mujdat Zeybel
Professor John Mathers
Steven White
et al.
Laser capture microdissection reveals cell-specific DNA methylation signatures in key fibrosis modifier genes in chronic liver disease2015
Dr Eva Moran Salvador
Dr Pier Paoli
Dr Graham Smith
Dr Agata Page
Rachel Howarth
et al.
MeCP2 exerts global control over the myofibroblast transcriptome and reveals new regulators of fibrosis2015
Dr Caroline Wilson
Dr Diana Jurk
Nicola Fullard
Paul Banks
Dr Agata Page
et al.
NFkB1 is a suppressor of neutrophil-driven hepatocellular carcinoma2015
Laura Corbett
Professor Jelena Mann
Professor Derek Mann
Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells2015
John Moir
Professor Jelena Mann
Steven White
The role of pancreatic stellate cells in pancreatic cancer2015
Dr Phillip Probert
Dr Mohammed Ebrahimkhani
Professor Fiona Oakley
Professor Jelena Mann
Professor Alastair Burt
et al.
A reversible model for periportal fibrosis and a refined alternative to bile duct ligation2014
Dr Anna Moles Fernandez
Dr Lindsay Murphy
Dr Caroline Wilson
Dr Jayshree Bagchi Chakraborty
Christopher Fox
et al.
A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse2014
John Moir
Steven White
Professor Jelena Mann
Arrested development and the great escape - The role of cellular senescence in pancreatic cancer2014
Laura Corbett
Professor Jelena Mann
Professor Derek Mann
Canonical vs non-canonical Wnt signalling2014
Dr Diana Jurk
Dr Caroline Wilson
Dr Joao Passos
Professor Fiona Oakley
Clara Correia Melo
et al.
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice2014
Dr Mujdat Zeybel
Dr Timothy Hardy
Christopher Fox
Dr Steven Masson
Professor Derek Mann
et al.
Differential DNA methylation of genes involved in fibrosis progression in NAFLD and ALD2014
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
Folfox induced sinusoidal obstruction syndrome (SOS) is a potentially reversible condition2014
Dr Katherine Crossland
Dr Mario Abinun
Professor Andrew Gennery
Professor Jelena Mann
Dr Dennis Lendrem
et al.
Gain-of-function stat1 mutation impairs stat3 function predisposing to chronic mucocutaneous candidiasis2014
Wona Suwara
Dr Nicola Green
Dr Lee Borthwick
Professor Jelena Mann
Emeritus Professor Nick Europe-Finner
et al.
IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts2014
Dr Caroline Wilson
Professor Jelena Mann
Dr Meagan Walsh
Professor Fiona Oakley
Professor Matthew Wright
et al.
Quiescent Hepatic Stellate Cells Functionally Contribute to the Hepatic Innate Immune Response via TLR32014
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
An experimental MODEL study to investigate the pathogenesis of oxaliplatin-induced liver injury2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
An experimental study to identify the potential role of pharmacogenomics in determining the occurrence of oxaliplatin-induced liver injury2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Antioxidant therapy is able to prevent the development of oxaliplatin induced sinusoidal obstruction syndrome2013
Dr Lindsay Murphy
Dr Jayshree Bagchi Chakraborty
Professor Jelena Mann
Professor Fiona Oakley
Professor Derek Mann
et al.
Deficient Neutrophil Recruitment into the Liver Parenchyma after an Acute CCl4 Challenge does not affect Fibrogenesis2013
Dr Mujdat Zeybel
Professor Derek Mann
Professor Jelena Mann
Epigenetic modifications as new targets for liver disease therapies2013
Joanna GÓRNIAK
Dr Sabine Langie
Professor Thomas von Zglinicki
Professor Jelena Mann
Professor John Mathers
et al.
Epigenetic regulation of DNA base excision repair during ageing and dietary restriction2013
Professor Jelena Mann
Professor Derek Mann
Epigenetic regulation of wound healing and fibrosis2013
Professor Derek Mann
Professor Jelena Mann
Ethanol Stimulates Production of Extracellular Matrix Proteins in Hepatic Stellate Cells2013
Dr John Petrie
Dr Ziad Al-Oanzi
Dr Catherine Arden
Dr Susan Tudhope
Professor Jelena Mann
et al.
Glucose induces protein targeting to glycogen in hepatocytes by fructose 2,6-bisphosphate-mediated recruitment of MondoA to the promoter2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Identification of molecular pathways implicated in the pathogenesis of oxaliplatin induced sinusoidal obstruction syndrome2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Is FOLFOX induced sinusoidal obstruction syndrome (SOS) a potentially reversible condition?2013
Stuart Robinson
Professor Jelena Mann
Professor John Mathers
Professor Alastair Burt
Professor Fiona Oakley
et al.
Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model2013
Stuart Robinson
Professor Derek Mann
Professor Derek Manas
Professor Fiona Oakley
Professor Jelena Mann
et al.
The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndrome2013
Laura Corbett
Professor Jelena Mann
Professor Derek Mann
The Wnt Pathway in Hepatic Stellate Cells: Canonical vs. Non-Canonical Signalling2013
Dr Maria Perugorria
Dr Lindsay Murphy
Dr Nicola Fullard
Dr Caroline Wilson
Professor Fiona Oakley
et al.
Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor-induced TIMP-1 gene transcription in hepatic stellate cells in mice2013
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Alastair Burt
Professor Derek Mann
et al.
An experimental study to determine the pathogenesis of oxaliplatin induced sinusoidal obstruction syndrome2012
Shilu Amin
Dr Meagan Walsh
Dr Caroline Wilson
Dr Elaine Willmore
Professor Derek Mann
et al.
Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL2012
Stuart Robinson
Professor Jelena Mann
Professor Alastair Burt
Professor Derek Manas
Professor Derek Mann
et al.
Does a pro-thrombotic environment contribute to the development of chemotherapy associated liver injury in patients with colorectal liver metastases?2012
Dr Mujdat Zeybel
Dr Meagan Walsh
Professor Derek Mann
Professor Jelena Mann
DZNep attenuates liver fibrosis by blocking EZH2 and H3K27me32012
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Expression of the copper export transporter atpase 7B correlates with tissue specific injury in a murine model of colorectal liver metastases2012
Stuart Robinson
Professor Jelena Mann
Professor Derek Manas
Professor Derek Mann
Steven White
et al.
Gene expression in oxaliplatin related sinusoidal obstruction syndrome2012
Dr Maria Perugorria
Dr Mujdat Zeybel
Mark Walsh
Shilu Amin
Professor Alastair Burt
et al.
Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation2012
Wona Suwara
Dr Lee Borthwick
Dr Rahul Mahida
Dr Nicola Green
Aaron Gardner
et al.
Interleukin-1 Alpha (IL-1α) Released from Injured Lung Epithelium is a Critical Alarmin Driving Activation of a Potent Inflammatory Phenotype in Lung Fibroblasts2012
Dr Mujdat Zeybel
Dr Timothy Hardy
Frances Wong
Professor John Mathers
Christopher Fox
et al.
Multigenerational epigenetic adaptation of the hepatic wound-healing response2012
Dr Caroline Wilson
Professor Fiona Oakley
Professor Jelena Mann
Professor Derek Mann
NF-kappa B1-/- suppresses ageing and carcinogen-induced hepatocellular carcinoma by limiting neutrophil accumulation and ROS production2012
Professor Derek Mann
Professor Jelena Mann
Rosmarinic acid and baicalin epigenetically derepress peroxisomal proliferator-activated receptor gamma in hepatic stellate cells for their antifibrotic effect2012
Dr Graeme Hewitt
Dr Diana Jurk
Francisco Marques
Clara Correia Melo
Dr Timothy Hardy
et al.
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence2012
Silvia Gaspar Pereira
Dr Nicola Fullard
Aidan Maxwell
Dr Lindsay Murphy
Dr Ralf Bauer
et al.
The NF-κB Subunit c-Rel Stimulates Cardiac Hypertrophy and Fibrosis2012
Professor Derek Mann
Professor Jelena Mann
Epigenetic cell fate regulation of hepatic stellate cells2011
Dr Maria Perugorria
Dr Caroline Wilson
Dr Mujdat Zeybel
Shilu Amin
Professor Fiona Oakley
et al.
Expression profiling of epigenetic regulators identifies ASH1 as a key activator of pro-fibrogenic genes2011
Stuart Robinson
Professor Jelena Mann
Professor Alastair Burt
Professor Derek Manas
Professor Derek Mann
et al.
Pathogenesis of chemotherapy associated liver injury prior to major hepatic resection2011
Dr Mujdat Zeybel
Professor Fiona Oakley
Professor Alastair Burt
Professor Derek Mann
Professor Jelena Mann
et al.
Protective adaptation to liver fibrosis in a single generation by heritable epigenetic modifications2011
Dr Mohammed Ebrahimkhani
Professor Fiona Oakley
Dr Lindsay Murphy
Professor Jelena Mann
Dr Maria Perugorria
et al.
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease2011
Monika Suwara
Dr Rahul Mahida
Dr Lee Borthwick
Professor Jelena Mann
Emeritus Professor Nick Europe-Finner
et al.
The Epithelial Alarmin, Interleukin 1 alpha (IL-1 alpha), Is a Potential Fibrogenic Factor in Bronchiolitis Obliterans Syndrome (BOS)2011
Dr Maria Perugorria
Professor Fiona Oakley
Professor Jelena Mann
Professor Derek Mann
TREM-2 expression is induced during the regeneration phase of liver injury and acts as a negative regulator of neutrophillic infiltration and hepatocyte proliferation2011
Dr Stuart Kendrick
Dr Graeme O'Boyle
Professor Jelena Mann
Dr Mujdat Zeybel
Dr Jeremy Palmer
et al.
Acetate, the Key Modulator of Inflammatory Responses in Acute Alcoholic Hepatitis2010
Professor Jelena Mann
Professor Derek Mann
Allele-Specific Regulation of Matrix Metalloproteinase-3 Gene by Transcription Factor NF kappa B2010
Professor Jelena Mann
Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter2010
Professor Jelena Mann
Professor Fiona Oakley
Professor Alastair Burt
Professor Derek Mann
Epigenetic regulation of pro-fibrogenic genes involved in hepatic stellate cell activation and liver fibrosis2010
Monika Suwara
Dr Lee Borthwick
Professor Jelena Mann
Professor Andrew Fisher
Professor Derek Mann
et al.
IL-1 IS A KEY EPITHELIAL ALARMIN WHICH PROMOTES FIBROBLAST ACTIVATION2010
Harriet Purvis
Dr Jeroen Stoop
Professor Jelena Mann
Steven Woods
Anne Kozijn
et al.
Low strength T-cell activation promotes Th17 responses2010
Dr Jeroen Stoop
Professor Jelena Mann
Steven Woods
Anne Kozijn
Professor Sophie Hambleton
et al.
Low-strength T-cell activation promotes Th17 responses2010
Professor Jelena Mann
Aidan Maxwell
Professor Fiona Oakley
Professor Derek Mann
MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis2010
Professor Jelena Mann
Professor Fiona Oakley
Professor Alastair Burt
Professor Derek Mann
NF-KB1 (p50) protects against growth of hepatocellular carcinoma by suppressing ROS, inhibiting hepatic phospho-Stat3 and stimulating Phospho-p38 alpha2010
Professor Jelena Mann
Regulation of NF-kappa B responses by epigenetic suppression of I kappa B alpha expression in HCT116 intestinal epithelial cells2010
Professor Derek Mann
Professor Jelena Mann
Rosmarinic acid lifts PPAR gamma epigenetic repression and restores stellate cell quiescence via induction of MIR132 and MIR137 and suppression of MeCP2 and EZH22010
Dr Roben Gieling
Dr Ahmed Elsharkawy
Dr David Cowie
Professor Matthew Wright
Dr Mohammed Ebrahimkhani
et al.
The c-Rel Subunit of Nuclear Factor-κB Regulates Murine Liver Inflammation, Wound-Healing, and Hepatocyte Proliferation2010
Dr Ahmed Elsharkawy
Professor Fiona Oakley
Professor Derek Mann
Professor Jelena Mann
The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes2010
Dr Maria Perugorria
Professor Fiona Oakley
Professor Jelena Mann
Professor Derek Mann
TREM-2 is induced in liver injury and is a suppressor of neutrophillic inflammation and hepatocyte proliferation2010
Professor Jelena Mann
Professor Derek Mann
Epigenetic Relay Controls Expression of the Master Fibrogenic and Metabolic Regulator PPAR Gamma and is Essential for Actovation of Hepatic Stellate Cells2009
Professor Jelena Mann
Xin Xu
Professor Fiona Oakley
Aidan Maxwell
Dr Ahmed Elsharkawy
et al.
Epigenetically Inherited Resistance to Liver Fibrosis2009
Aidan Maxwell
Professor Derek Mann
Professor Jelena Mann
Innate Immune Functions for Hepatic Stellate2009
Professor Jelena Mann
Professor Derek Mann
Transcriptional regulation of hepatic stellate cells2009
Professor Derek Mann
Professor Jelena Mann
Epigenetic regulation of hepatic stellate cell activation2008
Professor Jelena Mann
Epigenetic Regulation of ZAP70 in Chronic Lymphocytic Leukemia2008
Dr Ahmed Elsharkawy
Professor Jelena Mann
Professor Derek Mann
Phosphorylation of serine 343 on the NF-kappa B P50 subunit is a pivotal regulator of inflammation2008
Professor Jelena Mann
ZAP70 in chronic lymphocytic leukaemia2008
Professor Derek Mann
Professor Jelena Mann
Epigenetic regulation of hepatic stellate cell activation2007
Dr Stuart Kendrick
Dr Graeme O'Boyle
Professor Jelena Mann
Professor David Jones
Professor Chris Day
et al.
Ethanol-induced histone acetylation: A novel mechanism for enhancement of inflammation in alcoholic hepatitis?2007
Professor Jelena Mann
Professor Fiona Oakley
Dr Ahmed Elsharkawy
Professor Derek Mann
Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis2007
Professor Fiona Oakley
Professor Jelena Mann
Professor Derek Mann
JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation2006
Professor Jelena Mann
Professor Derek Mann
Functional Analysis of HIV Type 1 Nef Reveals a Role for PAK2 as a Regulator of Cell Phenotype and Function in the Murine Dendritic Cell Line, DC2.42005
Professor Fiona Oakley
Professor Jelena Mann
Professor Simi Ali
Professor Derek Mann
Nuclear Factor-κB1 (p50) Limits the Inflammatory and Fibrogenic Responses to Chronic Injury2005
Professor Jelena Mann
Professor Derek Mann
A failure of transforming growth factor-beta1 negative regulation maintains sustained NF-kappaB activation in gut inflammation2004
Professor Fiona Oakley
Professor Jelena Mann
Professor Derek Mann
Basal Expression of IκBα Is Controlled by the Mammalian Transcriptional Repressor RBP-J (CBF1) and Its Activator Notch12003
Professor Jelena Mann
Professor Fiona Oakley
Professor Derek Mann
CD40 Induces Interleukin-6 Gene Transcription in Dendritic Cells REGULATION BY TRAF2, AP-1, NF-κB, AND CBF12002
Professor Jelena Mann
Professor Derek Mann
JunD Regulates Transcription of the Tissue Inhibitor of Metalloproteinases-1 and Interleukin-6 Genes in Activated Hepatic Stellate Cells2001