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Browsing publications by Professor Nicola Curtin

Newcastle AuthorsTitleYearFull text
Lucy Gentles
Bojidar Goranov
Elizabeth Matheson
Dr Ashleigh Herriott
Dr Angelika Kaufmann
et al.
Exploring the frequency of Homologous Recombination DNA Repair Dysfunction in Multiple Cancer Types2019
Lucy Gentles
Liz Matheson
Dr Nicholas Bown
Alice Bradbury
Maryam Zanjirband Zanjirband
et al.
Characterization and drug sensitivity of a novel human overian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor2018
Dr Asima Mukhopadhyay
Dr Yvette Drew
Liz Matheson
Dr Mo Salehan
Lucy Gentles
et al.
Evaluating the potential of kinase inhibitors to suppress DNA repair and sensitise ovarian cancer cells to PARP inhibitors2018
Dr Sarah Fordham
Dr Helen Blair
Dr Claire Elstob
Professor Ruth Plummer
Dr Yvette Drew
et al.
Inhibition of ATR acutely sensitises acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase2018
Professor Nicola Curtin
Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases2018
Fiona Middleton
Professor Nicola Curtin
The impact of p53 dysfunction in ATR inhibitor cytotoxicity and chemo-and radiosensitisation2018
Judith Unterlass
Dr Arnaud Basle
Dr Julie Tucker
Dr Celine Cano
Professor Martin Noble
et al.
Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer2018
Lucy Gentles
Dr Calum Kirk
Huw Thomas
Professor Steve Wedge
Professor Nicola Curtin
et al.
An investigation of the effect of tissue ischaemia upon DNA damage protein markers in ovarian cancer2017
Maryam Zanjirband Zanjirband
Professor Nicola Curtin
Professor John Lunec
Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer2017
Dr Aiste McCormick
Dr Peter Donoghue
Michelle Dixon
Dr Rachel O'Donnell
James Murray
et al.
Ovarian Cancers Harbour Defects in Non-Homologous End Joining Resulting in Resistance to Rucaparib2017
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