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Synthesis of an arabinofuranosyl disaccharide photoaffinity probe for arabinosyltransferase activity in Mycobacterium tuberculosis

Lookup NU author(s): Dr Sudagar Gurcha, Professor Del Besra

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Abstract

(5-Azidonaphthalene-1-sulfonamidoethyl)- 5-O-(alpha-arabinofuranosyl)-alpha-D-arabino furano side 1 was synthesized as a photoaffinity probe for the determination of arabinosyl transferase activity and for the identification of binding and functional sites in Mycobacterium tuberculosis. (C) 2002 Elsevier Science Ltd. All rights reserved.

Publication metadata

Author(s): Pathak AK, Pathak V, Gurcha SS, Besra GS, Reynolds RC

Publication type: Article

Publication status: Published

Journal: Bioorganic & Medicinal Chemistry Letters

Year: 2002

Volume: 12

Issue: 19

Pages: 2749-2752

ISSN (print): 0960-894X

ISSN (electronic): 1464-3405

Publisher: Pergamon

URL: http://dx.doi.org/10.1016/S0960-894X(02)00536-X

DOI: 10.1016/S0960-894X(02)00536-X

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