Lookup NU author(s): Professor Robin Henderson,
Professor Richard Boys
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We adopt a hidden state approach for the analysis of longitudinal data subject to dropout. Motivated by two applied studies, we assume that subjects can move between three states: stable, crisis, dropout. Dropout is observed but the other two states are not. During a possibly transient crisis state both the longitudinal response distribution and the probability of dropout can differ from those for the stable state. We adopt a linear mixed effects model with subject-specific trajectories during stable periods and additional random jumps during crises. We place the model in the context of Rubin’s taxonomy and develop the associated likelihood. The methods are illustrated using the two motivating examples.
Author(s): Spagnoli A, Henderson R, Boys RJ, Houwing-Duistermaat JJ
Publication type: Article
Journal: Statistics and Probability Letters
Print publication date: 17/02/2011
ISSN (print): 0167-7152
Publisher: Elsevier BV
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