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Alternatives to Lung Transplantation: Treatment of Pulmonary Arterial Hypertension

Lookup NU author(s): Emeritus Professor Nick Europe-Finner

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Abstract

The development of targeted therapies for pulmonary arterial hypertension currently based on prostaglandin, nitric oxide, and endothelin pathways has resulted in major advances in the treatment of patients with pulmonary arterial hypertension. This article reviews the current evidence that supports both the use of mono- and combination therapy. The article also considers the role of atrial septostomy in the treatment of pulmonary arterial hypertension, particularly as a bridge to transplantation. Finally, the article provides a review of the role and outcomes of pulmonary thromboendartertectomy for patients with chronic thromboennbolic pulmonary hypertension.

Publication metadata

Author(s): Corris PA

Publication type: Article

Publication status: Published

Journal: Clinics in Chest Medicine

Year: 2011

Volume: 32

Issue: 2

Pages: 399-410

Print publication date: 19/04/2011

ISSN (print): 0272-5231

ISSN (electronic): 1557-8216

Publisher: WB Saunders Co.

URL: http://dx.doi.org/10.1016/j.ccm.2011.02.015

DOI: 10.1016/j.ccm.2011.02.015

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