Lookup NU author(s): Dr Rebeca Gonzalez,
Dr Samson Patole,
Professor Bernard Connolly,
Professor Andrew Houlton,
Dr Ben Horrocks,
Dr Andrew Pike
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Self-complementary oligonucleotides were synthesized at atomically-flat Si(111) surfaces and their hybridization reaction was studied using atomic force microscopy. Annealing these surfaces in aqueous media, in the absence of any other reagents or DNA, resulted in a self-organization process in which hybridization produced well-defined features in the AFM images. By varying the surface coverage of DNA we provide evidence that the features observed are due to inter-strand rather than intra-strand hybridization reactions.
Author(s): Carlsson S, Gonzalez R, O'Farrell N, Patole SN, Connolly BA, Houlton A, Horrocks BR, Pike A
Publication type: Article
Journal: Science of Advanced Materials
Print publication date: 01/06/2011
ISSN (print): 1947-2935
ISSN (electronic): 1947-2943
Publisher: American Scientific Publishers
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