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Study on the interaction between gelatin and polyurethanes derived from fatty acids

Lookup NU author(s): Dr Ana Ferreira-Duarte

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Abstract

In this study, gelatin was blended to proprietary noncytotoxic polyurethanes (PU) derived from vegetable oils with different weight ratios, as material for the preparation of novel biomedical products. The PU/gelatin blends were characterized for their morphology through scanning electron microscopy. Mechanical and thermal properties, chemical interactions between components, degradation behavior, surface properties, cell adhesion, and bioactivity were investigated as a function of the protein content. Higher blend miscibility was observed for the amorphous PUs, derived from oleic acid. Properties of PU/gelatin films were strongly influenced by the concentration of gelatin in the films. Gelatin enhanced the hydrophilicity, bioactivity, and cell adhesion of PUs


Publication metadata

Author(s): González-Paz RJ, Lligadas G, Ronda JC, Galià M, Ferreira AM, Boccafoschi F, Ciardelli C, Cádiz V

Publication type: Article

Journal: Journal of Biomedical Materials Research - Part A

Year: 2013

Volume: 101A

Issue: 4

Pages: 1036-1046

Online publication date: 11/09/2012

Acceptance date: 02/08/2012

Print publication date: 01/04/2013

ISSN (print): 1549-3296

ISSN (electronic): 1552-4965

Publisher: John Wiley & Sons, Inc.

URL: http://dx.doi.org/10.1002/jbm.a.34407

DOI: 10.1002/jbm.a.34407


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