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Evidence-based guidelines for treating bipolar disorder: Revised third edition recommendations from the British Association for Psychopharmacology

Lookup NU author(s): Professor Nicol Ferrier, Professor Hamish McAllister-Williams

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Abstract

The British Association for Psychopharmacology guidelines specify the scope and targets of treatment for bipolar disorder. The third version is based explicitly on the available evidence and presented, like previous Clinical Practice Guidelines, as recommendations to aid clinical decision making for practitioners: it may also serve as a source of information for patients and carers, and assist audit. The recommendations are presented together with a more detailed review of the corresponding evidence. A consensus meeting, involving experts in bipolar disorder and its treatment, reviewed key areas and considered the strength of evidence and clinical implications. The guidelines were drawn up after extensive feedback from these participants. The best evidence from randomized controlled trials and, where available, observational studies employing quasi-experimental designs was used to evaluate treatment options. The strength of recommendations has been described using the GRADE approach. The guidelines cover the diagnosis of bipolar disorder, clinical management, and strategies for the use of medicines in short-term treatment of episodes, relapse prevention and stopping treatment. The use of medication is integrated with a coherent approach to psychoeducation and behaviour change.


Publication metadata

Author(s): Goodwin GM, Haddad PM, Ferrier IN, Aronson JK, Barnes TRH, Cipriani A, Coghill DR, Fazel S, Geddes JR, Grunze H, Holmes EA, Howes O, Hudson S, Hunt N, Jones I, Macmillan IC, McAllister-Williams H, Miklowitz DR, Morriss R, Munafo M, Paton C, Saharkian BJ, Saunders KEA, Sinclair J, Taylor D, Vieta E, Young AH

Publication type: Review

Publication status: Published

Journal: Journal of Psychopharmacology

Year: 2016

Volume: 30

Issue: 6

Pages: 495-553

Print publication date: 01/06/2016

Online publication date: 15/03/2016

Acceptance date: 01/01/1900

ISSN (print): 0269-8811

ISSN (electronic): 1461-7285

Publisher: SAGE PUBLICATIONS LTD

URL: http://dx.doi.org/10.1177/0269881116636545

DOI: 10.1177/0269881116636545


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