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Resistance-modifying agents. 8. Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-alkenyl-, O6-cycloalkenyl-, and O6-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O6-(1-cyclopentenylmethyl) guanine

Lookup NU author(s): Professor Roger Griffin, Dr Christine Arris, Dr Christine Bleasdale, Professor Alan Calvert, Professor Nicola Curtin, Professor Herbie Newell, Professor Bernard Golding


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Publication metadata

Author(s): Griffin, R. J., Arris, C. E., Bleasdale, C. , Boyle, F., Calvert, A. H., Curtin, N. J., Dalby, C., Kanugula, S., Lembicz, N., Newell, D. R., Pegg, A., Golding, B. T.

Publication type: Article

Journal: Journal of Medicinal Chemistry

Year: 2000

Volume: 43

Issue: 22

Pages: 4071-4083

Print publication date: 02/11/2000

ISSN (print): 0022-2623

ISSN (electronic): 1520-4804


DOI: 10.1021/jm000961o

PubMed id: 11063604


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