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Lookup NU author(s): Professor Galip Akay, Dr Mark Birch, Dr Maria Bokhari, Dr Elif Erhan, Dr Bulent Keskinler
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Background of Phenomenon Based Bioprocess Intensification based on the behaviour of microorganisms within confined micro-environment is given. This type of bioprocess intensification provides more than 30 fold enhancement of bio-conversions compared with the existing technology. The underlying phenomenon was first observed in in-vitro culture of animal cells (tissue engineering). The technique requires the manufacture of (nano-structured) micro-porous cell support systems with a well prescribed micro-architecture and chemical structure. It appears that the bioprocess intensification technique described here is a consequence of bacterial support architecture and the presence of flow through the monolithic micro-bioreactor which results in mono-layer bacterial proliferation, absence of extra-cellular matrix and biofilm formation. © BHR Group 2005 Process Intensification 6.
Author(s): Akay G, Birch MA, Bokhari MA, Byron VJ, Erhan E, Keskinler B
Editor(s): Jansens, P., Stankiewicz, A., Green, A.
Publication type: Conference Proceedings (inc. Abstract)
Publication status: Published
Conference Name: Sustainable (Bio)Chemical Process Technology - Incorporating the 6th Intenational Conference on Process Intensification
Year of Conference: 2005
Pages: 347-353
Publisher: BHR Group
URL: http://www.bhrgroup.co.uk/confsite/pi05home.htm
Library holdings: Search Newcastle University Library for this item
ISBN: 9781855980686
