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Browsing publications by
Lan Wang
Newcastle Authors
Title
Year
Full text
Lan Wang
Professor Nilanjan Chakraborty
Effects of the cold wall boundary on the flame structure and flame speed in premixed turbulent combustion
2020
Daniel Wood
Svitlana Korolchuk
Dr Natalie Tatum
Lan Wang
Professor Jane Endicott
et al.
Differences in the conformational energy landscape of CDK1 and CDK2 suggest a mechanism for achieving selective CDK inhibition
2019
Stephanie Myers
Duncan Miller
Dr Lauren Molyneux
Dr Mercedeh Arasta
Dr Ruth Bawn
et al.
Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4
2019
Christopher Coxon
Dr Suzannah Harnor
Dr Mathew Martin
Dr Benoit Carbain
Professor Bernard Golding
et al.
Cyclin-Dependent Kinase (CDK) Inhibitors; Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines
2017
Dr Christopher Wong
Dr Ian Hardcastle
Christopher Matheson
Emeritus Professor Herbie Newell
Dr Mangaleswaran Sivaprakasam
et al.
Structure-guided design of purine-based probes for selective Nek2 inhibition
2017
Dr Gary Beale
Dr Emma Haagensen
Huw Thomas
Lan Wang
Charlotte Revill
et al.
Combined PI3K and CDK2 inhibition induces cell death and enhances
in vivo
anti-tumour activity in colorectal cancer
2016
Lan Wang
Emeritus Professor Herbie Newell
Professor Steve Wedge
Tumor cells with
KRAS
or
BRAF
mutations or
ERK5/MAPK7
amplification are not addicted to ERK5 activity for cell proliferation
2016
Dr Benoit Carbain
Dr Allyson Campbell
Dr Celine Cano
Professor Jane Endicott
Professor Bernard Golding
et al.
8-Substituted
O-6
-Cyclohexylmethylguanine CDK2 Inhibitors: Using Structure-Based Inhibitor Design to Optimize an Alternative Binding Mode
2014
Honorine Lebraud
Professor Bernard Golding
Elisa Meschini
Dr Celine Cano
Lan Wang
et al.
Anticancer agents targeted against cyclin-dependent kinase 2 (CDK2): Structure-based design of irreversible and reversible inhibitors
2014
Dr Mathew Martin
Elisa Meschini
Lan Wang
Dr Regina Mora Vidal
Tristan Reuillon
et al.
Identification and characterization of an irreversible inhibitor of CDK2
2014
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