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Browsing publications by
Dr Chiara Maniaci.
Newcastle Authors
Title
Year
Full text
Dr Chiara Maniaci
Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms
2022
Dr Chiara Maniaci
Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity
2021
Dr Chiara Maniaci
Understanding and improving the membrane permeability of VH032-based PROTACs.
2020
Dr Chiara Maniaci
Bifunctional chemical probes inducing protein-protein interactions.
2019
Dr Chiara Maniaci
Cereblon vs VHL: Hijacking E3 Ligases Against Each Other Using PROTACs.
2019
Dr Chiara Maniaci
Rapid and reversible knockdown of endogenously tagged endosomal proteins via an optimized HaloPROTAC degrader.
2019
Dr Chiara Maniaci
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7
2018
Dr Chiara Maniaci
Homo-PROTACs: Bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation.
2017